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Article

Accelerating effect of an MRL gene locus on the severity and onset of arthropathy in DBA/1 mice.

Arthritis and rheumatism - 1 Mar 2005

Oishi Hisashi, Miyazaki Tatsuhiko, Mizuki Shinichi, Kamogawa Junji, Lu Ling-Min, Tsubaki Takahito, Arita Norimasa, Ono Masao, Yamamoto Haruyasu, Nose Masato

Abstract excerpt

OBJECTIVE: To analyze the influence of the genetic background of an arthritis-prone strain of mice, MRL, on the spontaneous development of arthropathy in DBA/1 mice, which histopathologically resembles enthesopathy in humans, and to clarify the strain-specific gene loci and their interactions that confer susceptibility to arthropathy. METHODS: MRL, DBA/1, (MRL x DBA/1)F(1), and (MRL x DBA/1)F(2) intercross mice...

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PMID: 15751084
DOI: 10.1002/art.20956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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