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Article

Function associated transforming growth factor-beta gene polymorphism in chronic beryllium disease.

Journal of molecular medicine (Berlin, Germany) - 1 May 2005

Gaede Karoline I, Amicosante Massimo, Schürmann Manfred, Fireman Elisabeth, Saltini Cesare, Müller-Quernheim Joachim

Abstract excerpt

Chronic beryllium disease (CBD) is a rare occupational, granulomatous lung disease clinically resembling sarcoidosis. The immune response to beryllium is thought to depend on genetic susceptibility. Although a glutamic acid in position 69 of the human leukocyte antigen-DP beta chain (HLA-DPB1-Glu69) is associated with the development of CBD, it cannot fully explain susceptibility. It is likely that additionally...

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PMID: 15750822
DOI: 10.1007/s00109-004-0626-0

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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