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Article

TGF-beta 1 variants in chronic beryllium disease and sarcoidosis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2007

Jonth Alexas C, Silveira Lori, Fingerlin Tasha E, Sato Hiroe, Luby Julie C, Welsh Kenneth I, Rose Cecile S, Newman Lee S, du Bois Roland M, Maier Lisa A

Abstract excerpt

Evidence suggests a genetic predisposition to chronic beryllium disease (CBD) and sarcoidosis, which are clinically and pathologically similar granulomatous lung diseases. TGF-beta1, a cytokine involved in mediating the fibrotic/Th1 response, has several genetic variants which might predispose individuals to these lung diseases. We examined whether certain TGF-beta1 variants and haplotypes are found at higher...

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Identifiers

PMID: 17785866
DOI: 10.4049/jimmunol.179.6.4255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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