HLA-DRw52-associated DRB1 alleles: identification using polymerase chain reaction-amplified DNA, sequence-specific oligonucleotide probes, and a chemiluminescent detection system.

doi:10.1111/j.1399-0039.1992.tb01912.x

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Article

HLA-DRw52-associated DRB1 alleles: identification using polymerase chain reaction-amplified DNA, sequence-specific oligonucleotide probes, and a chemiluminescent detection system.

Tissue antigens - 1 Feb 1992

Shaffer A L, Falk-Wade J A, Tortorelli V, Cigan A, Carter C, Hassan K, Hurley C K

Abstract excerpt

Polymerase chain reaction (PCR) primers were designed to specifically amplify exon 2 of the DRw52-associated DRB1 alleles for subsequent typing by sequence-specific oligonucleotide probe (SSOP) hybridization and chemiluminescent detection. The DRw52 DRB1 group, encoding 22 of the 44 W.H.O. design...

Topics

Adult
Alleles
Base Sequence
DNA
Gene Amplification
HLA-DR Antigens
HLA-DR Serological Subtypes
HLA-DR3 Antigen
HLA-DR6 Antigen
HLA-DRB1 Chains
Histocompatibility Antigens Class II
Humans
Luminescent Measurements
Male

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Nucleic Acid Hybridization

Oligonucleotide Probes

Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 1574802
DOI: 10.1111/j.1399-0039.1992.tb01912.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1574802-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.