Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of exogenous protein in the egg white of transgenic chickens.

Nature biotechnology - 1 Apr 2002

Harvey Alex J, Speksnijder Gordon, Baugh Larry R, Morris Julie A, Ivarie Robert

Abstract excerpt

Using a replication-deficient retroviral vector based on the avian leukosis virus (ALV), we inserted into the chicken genome a transgene encoding a secreted protein, beta-lactamase, under the control of the ubiquitous cytomegalovirus (CMV) promoter. Biologically active beta-lactamase was secreted into the serum and egg white of four generations of transgenic chickens. The expression levels were similar in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to beta-Lactamases
Share to Bioreactors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chickens

Share to Genes, Reporter

Share to Genetic Vectors

Share to Transgenes

Source

Identifiers

PMID: 11923848
DOI: 10.1038/nbt0402-396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of exogenous protein in the egg white of transgenic chickens.PMID 11923848Read ↗

Consistent production of transgenic chickens using replication-deficient retroviral vectors and high-throughput screening procedures.Semantic proximity Read ↗

Replication-competent endogenous avian leukosis virus in commercial lines of meat chickens.Semantic proximity Read ↗

The 3D8 single chain variable fragment protein suppresses Newcastle disease virus transmission in transgenic chickensSemantic proximity Read ↗

Application of transgenesis in livestock for agriculture and biomedicineSemantic proximity Read ↗

Gene insertion: current progress and long-term goals.Semantic proximity Read ↗

Lysozyme transgenic Atlantic salmon (Salmo salar L.)Semantic proximity Read ↗

Survey of endogenous virus and TVB* receptor status of commercial chicken stocks supplying specific-pathogen-free eggs.Semantic proximity Read ↗

Analysis of an approach to oviduct-specific expression of modified chicken lysozyme genes.Semantic proximity Read ↗

Improving germline transmission efficiency in chimeric chickens using a multi-stage injection approachSemantic proximity Read ↗

Expression of the murine wild-type tyrosinase gene in transgenic rabbits.Semantic proximity Read ↗

Expression of recombinant human factor VIII in milk of several generations of transgenic rabbitsSemantic proximity Read ↗

Establishing a zebrafish transgenic line expressing tilapia lysozyme with enhanced antibacterial activitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.