Article
Diagnosis and Therapy of Acute Myeloid Leukemia in the Era of Molecular Risk Stratification.
Annual review of medicine - 1 Jan 2016
Komanduri Krishna V, Levine Ross L
Abstract excerpt
The diagnosis and risk stratification of acute myeloid leukemia (AML) primarily rely on morphologic analysis and assessment of karyotype by chromosome banding analysis. For decades, standard AML induction therapy has utilized the combination of anthracyclines and cytarabine. Despite the use of postremission therapy, less than half of patients with AML will be cured of their disease. Allogeneic hematopoietic stem...
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