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Article

Impaired Pavlovian fear extinction is a common phenotype across genetic lineages of the 129 inbred mouse strain.

Genes, brain, and behavior - 1 Nov 2009

Camp M, Norcross M, Whittle N, Feyder M, D'Hanis W, Yilmazer-Hanke D, Singewald N, Holmes A

Abstract excerpt

Fear extinction is impaired in psychiatric disorders such as post-traumatic stress disorder and schizophrenia, which have a major genetic component. However, the genetic factors underlying individual variability in fear extinction remain to be determined. By comparing a panel of inbred mouse strains, we recently identified a strain, 129S1/SvImJ (129S1), that exhibits a profound and selective deficit in Pavlovian...

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Identifiers

PMID: 19674120
DOI: 10.1111/j.1601-183X.2009.00519.x
PMCID: PMC2783364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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