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Article

The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 17 Apr 2013

Duman Joseph G, Tzeng Christopher P, Tu Yen-Kuei, Munjal Tina, Schwechter Brandon, Ho Tammy Szu-Yu, Tolias Kimberley F

Abstract excerpt

Excitatory synapses are polarized structures that primarily reside on dendritic spines in the brain. The small GTPase Rac1 regulates the development and plasticity of synapses and spines by modulating actin dynamics. By restricting the Rac1-guanine nucleotide exchange factor Tiam1 to spines, the...

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Identifiers

PMID: 23595754
DOI: 10.1523/JNEUROSCI.3978-12.2013
PMCID: PMC3670686

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23595754-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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