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Article

Regulation of large dense-core vesicle volume and neurotransmitter content mediated by adaptor protein 3.

Proceedings of the National Academy of Sciences of the United States of America - 27 Jun 2006

Grabner Chad P, Price Steven D, Lysakowski Anna, Cahill Anne L, Fox Aaron P

Abstract excerpt

Adaptor protein 3 (AP-3) is a vesicle-coat protein that forms a heterotetrameric complex. Two types of AP-3 subunits are found in mammalian cells. Ubiquitous AP-3 subunits are expressed in all tissues of the body, including the brain. In addition, there are neuronal AP-3 subunits that are thought to serve neuron-specific functions such as neurotransmitter release. In this study, we show that overexpression of...

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Identifiers

PMID: 16788073
DOI: 10.1073/pnas.0509844103
PMCID: PMC1502501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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