Article
Cholecystokinin (CCK) and the CCKA receptor gene polymorphism, and smoking behavior.
Psychiatry research - 28 Feb 2005
Takimoto Takahiro, Terayama Hayato, Waga Chikako, Okayama Takashi, Ikeda Kazutaka, Fukunishi Isao, Iwahashi Kazuhiko
Abstract excerpt
We analyzed genetic variants of the promoter region of the cholecystokinin (CCK; which modulates the release of dopamine) gene, and intron 1 and exon 5 of the CCKA receptor gene, and performed association analyses of nicotine dependence using an allele-specific amplification (ASA) method and PCR-RFLP methods. There was a significant difference between the current smoking and nonsmoking groups in the allele...
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