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Article

Association between the CCK-A receptor gene and panic disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2003

Ise Kiminobu, Akiyoshi Jotaro, Horinouchi Yukiko, Tsutsumi Takashi, Isogawa Koichi, Nagayama Haruo

Abstract excerpt

Cholecystokinin (CCK) is one of the most abundant neurotransmitter peptides in the brain. CCK appears to play an important role in the neurobiology of anxiety and panic disorders (PD) in both humans and animals. Recently, we reported that lack of CCKAR had a significant anxiogenic-like effect in rats. In this study, to investigate the role of CCKAR in PD, we compared the CCKAR gene in PD patients and normal...

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Source

Identifiers

PMID: 12627462
DOI: 10.1002/ajmg.b.10020

Genes

CCKAR
CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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