Article
Genetic polymorphism of the CCK gene in patients with alcohol withdrawal symptoms.
Alcoholism, clinical and experimental research - 1 Apr 2000
Okubo T, Harada S, Higuchi S, Matsushita S
Abstract excerpt
BACKGROUND: Cholecystokinin (CCK) is considered to play an important role in the central nervous system via its interaction with other neurotransmitters such as dopamine, serotonin, gamma-aminobutyric acid, substance P, and enkephalins. We investigated the relationship between the C to T substitution in the Sp1 binding cis-element of the CCK gene promoter region (at position -45 numbered from initiation codon)...
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