Article
MET and MYC cooperate in mammary tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America - 22 Mar 2005
Welm Alana L, Kim Suwon, Welm Bryan E, Bishop J Michael
Abstract excerpt
In human breast cancer, overexpression of the protooncogene MET is strongly associated with poor prognosis and high risk of metastasis. It stands out as a reliable prognostic indicator of survival and defines a set of tumors exclusive of those that express HER2 or hormone receptors. Studies have shown that overexpression of mutant forms of MET cause cancer in mice. However, MET mutations have not been found in...
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