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Article

Initiating oncogenic event determines gene-expression patterns of human breast cancer models

14 May 2002

Abstract excerpt

Molecular expression profiling of tumors initiated by transgenic overexpression of c-myc, c-neu, c-ha-ras, polyoma middle T antigen (PyMT) or simian virus 40 T/t antigen (T-ag) targeted to the mouse mammary gland have identified both common and oncogene-specific events associated with tumor formation and progression. The tumors shared great similarities in their gene-expression profiles as compared with the...

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Identifiers

PMID: 12011455
DOI: 10.1073/pnas.102172399

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