Article
From genotype to olfactory neuron phenotype: the role of the Olf-1-binding site.
Ciba Foundation symposium - 1 Jan 1993
Margolis F L, Kudrycki K, Stein-Izsak C, Grillo M, Akeson R
Abstract excerpt
The highly organized pattern of gene expression leading to the determination of cellular phenotype derives from the interplay between genetic and epigenetic factors. This is mediated in part by distinctive DNA sequence motifs present in the regulatory regions of various genes and the transcription factors with which they interact. The phenotype of olfactory neurons is determined in part by the selective...
Topics
- Animals
- Base Sequence
- Binding Sites
- DNA-Binding Proteins
- Genotype
- Humans
- Molecular Sequence Data
- Nerve Tissue Proteins
- Olfactory Receptor Neurons
- Organ Specificity
- Phenotype