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Article

Functional interaction of protein kinase CK2 and activating transcription factor 4 (ATF4), a key player in the cellular stress response.

Biochimica et biophysica acta - 1 Mar 2013

Ampofo Emmanuel, Sokolowsky Tasja, Götz Claudia, Montenarh Mathias

Abstract excerpt

Protein kinase CK2 is a pleiotropic enzyme, which is implicated in the regulation of numerous biological processes. It seems to regulate the various functions by binding to other proteins and by phosphorylation of many different substrates. Here, we identified the activating transcription factor 4 (ATF4), an essential component of the ER stress signaling, as a new binding partner and a new substrate of CK2 in...

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Source

Identifiers

PMID: 23123191
DOI: 10.1016/j.bbamcr.2012.10.025

Genes

ATF4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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