The death-inducing effect and genomic instability.

doi:10.1667/rr3312

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Article

The death-inducing effect and genomic instability.

Radiation research - 1 Mar 2005

Nagar Shruti, Morgan William F

Abstract excerpt

Exposure to ionizing radiation can induce a heritable change in the unirradiated progeny of irradiated cells. This non-targeted effect of ionizing radiation manifests as genomic instability, and although there is some debate as to the role of genomic instability in the carcinogenic process, it is thought by some to be an early step in radiation carcinogenesis. Although the mechanism of induction of genomic...

Topics

Animals
Biotinylation
Cell Death
Cell Line, Tumor
Cell Survival
Chromosomal Instability
Chromosome Aberrations
Chromosomes
Cricetinae
Culture Media
Culture Media, Conditioned
Cytogenetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

DNA

Genomic Instability

Humans

Hypoxanthine Phosphoribosyltransferase

In Situ Hybridization, Fluorescence

Micronucleus Tests

Source

Open in PubMed

Identifiers

PMID: 15733038
DOI: 10.1667/rr3312

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