Article
Damaging and protective cell signalling in the untargeted effects of ionizing radiation.
Mutation research - 2 Dec 2004
Coates Philip J, Lorimore Sally A, Wright Eric G
Abstract excerpt
The major adverse consequences of radiation exposures are attributed to DNA damage in irradiated cells that has not been correctly restored by metabolic repair processes. However, the dogma that genetic alterations are restricted to directly irradiated cells has been challenged by observations in which effects of ionizing radiation arise in non-irradiated cells. These, so called, untargeted effects are...
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