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Chromosomal instability and its relationship to other end points of genomic instability.

Cancer research - 15 Dec 1997

Limoli C L, Kaplan M I, Corcoran J, Meyers M, Boothman D A, Morgan W F

Abstract excerpt

Chromosomal destabilization is one end point of the more general phenomenon of genomic instability. We previously established that chromosomal instability can manifest in clones derived from single progenitor cells several generations after X-irradiation. To understand the potential relationship between chromosomal destabilization and the other end points of genomic instability, we generated a series of...

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PMID: 9407967

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