Chromosomal instability and its relationship to other end points of genomic instability.

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Article

Chromosomal instability and its relationship to other end points of genomic instability.

Cancer research - 15 Dec 1997

Limoli C L, Kaplan M I, Corcoran J, Meyers M, Boothman D A, Morgan W F

Abstract excerpt

Chromosomal destabilization is one end point of the more general phenomenon of genomic instability. We previously established that chromosomal instability can manifest in clones derived from single progenitor cells several generations after X-irradiation. To understand the potential relationship...

Topics

Animals
CHO Cells
Cell Death
Chromosome Aberrations
Chromosomes, Human, Pair 4
Cricetinae
DNA Repair
Gene Amplification
Genome
Humans
Hypoxanthine Phosphoribosyltransferase
Mutation
Phenotype
Sister Chromatid Exchange
X-Rays

Source

Open in PubMed

Identifiers

PMID: 9407967

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9407967-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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