Article
Inducible genomic instability: new insights into the biological effects of ionizing radiation.
Medicine, conflict, and survival - 1 Jan 2000
Wright E G
Abstract excerpt
The biological consequences of exposure to ionizing radiation include gene mutation, chromosome aberrations, malignant transformation and cell death. These effects are attributed to the production of irreversible damage at the time of the irradiation. However, there is now considerable evidence that cells that have survived irradiation may produce descendants in which a high frequency of de novo chromosome...
Topics
- Animals
- Cell Transformation, Neoplastic
- Chromosome Aberrations
- DNA Damage
- Humans
- Models, Genetic
- Mutation
- Radiation Injuries
