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Article

Rat/MgrA, a regulator of autolysis, is a regulator of virulence genes in Staphylococcus aureus.

Infection and immunity - 1 Mar 2005

Ingavale Susham, van Wamel Willem, Luong Thanh T, Lee Chia Y, Cheung Ambrose L

Abstract excerpt

We have previously identified mgrA (rat) as a regulator of autolysis in Staphylococcus aureus. Besides its effect on autolytic activity, we recently found alterations in the expression of regulator and target virulence genes in the mgrA mutant. Northern analysis and transcription fusion assays showed that inactivation of mgrA has led to the downregulation of RNAIII of agr and hla and upregulation of sarS and spa....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15731040
DOI: 10.1128/IAI.73.3.1423-1431.2005
PMCID: PMC1064946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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