Article
The two‐component system ArlS–ArlR is a regulator of virulence gene expression in <i>Staphylococcus aureus</i>
1 Jul 2001
Abstract excerpt
Staphylococcus aureus is a major human pathogen that produces many virulence factors in a temporally regulated manner controlled by at least two global virulence regulatory loci (agr and sarA). We identified previously a two-component system, ArlS-ArlR, that modifies the activity of extracellular serine protease and may be involved in virulence regulation. Here, we show that mutations in either arlR or arlS...
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