Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ets-2 repressor factor recruits histone deacetylase to silence human cytomegalovirus immediate-early gene expression in non-permissive cells

19 Feb 2005

Abstract excerpt

Previous work from this laboratory has shown that expression of human cytomegalovirus (HCMV) immediate-early (IE) genes from the major immediate-early promoter (MIEP) is likely to be regulated by chromatin remodelling around the promoter affecting the acetylation state of core histone tails. The HCMV MIEP contains sequences that bind cellular transcription factors responsible for its negative regulation in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15722512
DOI: 10.1099/vir.0.80352-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ets-2 repressor factor recruits histone deacetylase to silence human cytomegalovirus immediate-early gene expression in non-permissive cellsPMID 15722512Read ↗

Ets-2 Repressor Factor (ERF) mediates repression of the human cytomegalovirus major immediate-early promoter in undifferentiated non-permissive cellsSemantic proximity Read ↗

Functional interaction of the human cytomegalovirus IE2 protein with histone deacetylase 2 in infected human fibroblastsSemantic proximity Read ↗

Autorepression of the Human Cytomegalovirus Major Immediate-Early Promoter/Enhancer at Late Times of Infection Is Mediated by the Recruitment of Chromatin Remodeling Enzymes by IE86Semantic proximity Read ↗

Control of Immediate Early Gene Expression for Human Cytomegalovirus ReactivationSemantic proximity Read ↗

Human cytomegalovirus immediate-early 1 protein facilitates viral replication by antagonizing histone deacetylation.Semantic proximity Read ↗

Lytic infection of permissive cells with human cytomegalovirus is regulated by an intrinsic ‘pre-immediate-early’ repression of viral gene expression mediated by histone post-translational modificationSemantic proximity Read ↗

A cis-acting element in the major immediate-early (IE) promoter of human cytomegalovirus is required for negative regulation by IE2Semantic proximity Read ↗

Repression of the major immediate early promoter of human cytomegalovirus allows transcription from an alternate promoter.Semantic proximity Read ↗

Regulation of Human Cytomegalovirus Transcription in Latency: Beyond the Major Immediate-Early PromoterSemantic proximity Read ↗

Chromatin control of human cytomegalovirus infectionSemantic proximity Read ↗

Reactivation of the Human Cytomegalovirus Major Immediate-Early Regulatory Region and Viral Replication in Embryonal NTera2 Cells: Role of Trichostatin A, Retinoic Acid, and Deletion of the 21-Base-Pair Repeats and ModulatorSemantic proximity Read ↗

Regulation of the MIE Locus During HCMV Latency and ReactivationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.