Article
A nonsynonymous polymorphism in the human fatty acid amide hydrolase gene did not associate with either methamphetamine dependence or schizophrenia.
Neuroscience letters - 16 Mar 2005
Morita Yukitaka, Ujike Hiroshi, Tanaka Yuji, Uchida Naohiko, Nomura Akira, Ohtani Kyohei, Kishimoto Makiko, Morio Akiko, Imamura Takaki, Sakai Ayumu, Inada Toshiya, Harano Mutsuo, Komiyama Tokutaro, Yamada Mitsuhiko, Sekine Yoshimoto, Iwata Nakao, Iyo Masaomi, Sora Ichiro, Ozaki Norio, Kuroda Shigetoshi
Abstract excerpt
Genetic contributions to the etiology of substance abuse and dependence are topics of major interest. Acute and chronic cannabis use can produce drug-induced psychosis resembling schizophrenia and worsen positive symptoms of schizophrenia. The endocannabinoid system is one of the most important neural signaling pathways implicated in substance abuse and dependence. The fatty acid amide hydrolase (FAAH) is a...
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