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Article

The genetic basis of the endocannabinoid system and drug addiction in humans.

Journal of psychopharmacology (Oxford, England) - 1 Jan 2012

López-Moreno Jose Antonio, Echeverry-Alzate Victor, Bühler Kora-Mareen

Abstract excerpt

The cannabinoid receptor (CNR1) and the fatty acid amide hydrolase (FAAH) genes are located on chromosomes 6 and 1 in the 6q15 and 1p33 cytogenetic bands, respectively. CNR1 encodes a seven-transmembrane domain protein of 472 amino acids, whereas FAAH encodes one transmembrane domain of 579 amino acids. Several mutations found in these genes lead to altered mRNA stability and transcription rate or a reduction of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21937688
DOI: 10.1177/0269881111416689

Genes

FAAH
CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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