Article
Association of FAAH p.Pro129Thr and COMT p.Ala72Ser with schizophrenia and comorbid substance use through next-generation sequencing: an exploratory analysis.
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) - 1 Jan 2000
Martínez-Magaña José J, Genis-Mendoza Alma D, González-Covarrubias Vanessa, Juárez-Rojop Isela E, Tovilla-Zárate Carlos A, Soberón Xavier, Lanzagorta Nuria, Nicolini Humberto
Abstract excerpt
OBJECTIVE: Individuals with schizophrenia and substance use disorders have a poor prognosis and increased psychiatric symptoms. The present study aimed to explore the association of 106 genes in individuals with schizophrenia and comorbid substance use through a next-generation sequencing (NGS) analysis and different in silico algorithms. METHODS: We included 105 individuals diagnosed with schizophrenia and a...
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