Prolonged clinically asymptomatic evolution after HIV-1 infection is marked by the absence of complement C4 null alleles at the MHC.

doi:10.1111/j.1365-2249.1992.tb03067.x

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Article

Prolonged clinically asymptomatic evolution after HIV-1 infection is marked by the absence of complement C4 null alleles at the MHC.

Clinical and experimental immunology - 1 May 1992

Hentges F, Hoffmann A, Oliveira de Araujo F, Hemmer R

Abstract excerpt

The length of time after which persons infected with HIV-1 progress to AIDS is variable. Certain alleles at the MHC have been shown to influence negatively the clinical outcome of HIV-1-infected persons and to be associated with special clinical manifestations. We investigated the MHC class I, cl...

Topics

Acquired Immunodeficiency Syndrome
Adult
Alleles
Complement C4
Female
Gene Frequency
HIV Infections
HIV-1
HLA Antigens
Humans
Major Histocompatibility Complex
Male
Middle Aged
Time Factors

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