Assays for complement proteins encoded in the class III region of human MHC.

doi:10.1002/0471142735.im1307s67

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Article

Assays for complement proteins encoded in the class III region of human MHC.

Current protocols in immunology - 1 Jul 2005

Varga Lilian, Füst George

Abstract excerpt

Investigation of the complement proteins encoded in the class III region of the human MHC isclinically significant. A low level of components that make up the classical pathway is indicative of an underlying in vivo complement activation or primer complement deficiency. Hemolytic tests of C4 and C2 described are the only methods that allow quantitification of the functional complement proteins. The application of...

Topics

Alleles
Animals
Biological Assay
Complement C2
Complement C4
Complement Factor B
Complement Hemolytic Activity Assay
Complement System Proteins
Electrophoresis, Agar Gel
Electrophoretic Mobility Shift Assay
Erythrocytes
Guinea Pigs
Hemolysis
Humans
Immunoelectrophoresis
Major Histocompatibility Complex
Phenotype
Sheep

Source

Open in PubMed

Identifiers

PMID: 18432941
DOI: 10.1002/0471142735.im1307s67

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