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Article

Signal transducer and activator of transcription (STAT) signalling and T‐cell lymphomas

17 Feb 2005

Abstract excerpt

Interaction of cytokines with their cognate receptors leads to the activation of latent transcription factors - the signal transducers and activators of transcription (STAT) proteins - whose biological activities ultimately regulate many critical aspects of cell growth, survival and differentiation. Dysregulation of the JAK-STAT pathway is frequently observed in many primary human tumours, reflecting the...

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Share to Cytokine Signaling Pathways and Interactions
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15720432
DOI: 10.1111/j.1365-2567.2005.02091.x

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