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Article

Activation of the vrg6 promoter of Bordetella pertussis by RisA.

Journal of bacteriology - 1 Mar 2005

Cróinín Tadhg O, Grippe Vanessa K, Merkel Tod J

Abstract excerpt

The BvgAS two-component system positively regulates the expression of the virulence genes of Bordetella pertussis and negatively regulates a second set of genes whose function is unknown. The BvgAS-mediated regulation of the bvg-repressed genes is accomplished through the activation of expression of the negative regulator, BvgR. A second two-component regulatory system, RisAS, is required for expression of the...

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Share to Bacterial Proteins
Share to Bordetella pertussis
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 15716435
DOI: 10.1128/JB.187.5.1648-1658.2005
PMCID: PMC1063992

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Activation of the vrg6 promoter of Bordetella pertussis by RisA.PMID 15716435Read ↗

Analysis of bvgR expression in Bordetella pertussis.Semantic proximity Read ↗

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A vir-repressed gene of Bordetella pertussis is required for virulence.Semantic proximity Read ↗

Activation of Bvg-Repressed Genes in Bordetella pertussis by RisA Requires Cross Talk from Noncooperonic Histidine Kinase RisK.Semantic proximity Read ↗

Identification and genomic organization of gene loci negatively controlled by the virulence regulatory BvgAS two-component system in Bordetella bronchiseptica.Semantic proximity Read ↗

The BvgAS Regulon of Bordetella pertussisSemantic proximity Read ↗

Mechanisms of bordetella pathogenesisSemantic proximity Read ↗

Differential regulation of Bordetella pertussis virulence factors.Semantic proximity Read ↗

Neither the Bvg- phase nor the vrg6 locus of Bordetella pertussis is required for respiratory infection in mice.Semantic proximity Read ↗

Mutations in the linker region of BvgS abolish response to environmental signals for the regulation of the virulence factors in Bordetella pertussis.Semantic proximity Read ↗

The proline residue at position 319 of BvgS is essential for BvgAS activation in Bordetella pertussis.Semantic proximity Read ↗

Comparative analysis of the virulence control systems of Bordetella pertussis and Bordetella bronchiseptica.Semantic proximity Read ↗

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