Article
Maintenance of cell integrity in the gas1 mutant of Saccharomyces cerevisiae requires the Chs3p-targeting and activation pathway and involves an unusual Chs3p localization.
Yeast (Chichester, England) - 30 Sept 2002
Carotti Cristina, Ferrario Laura, Roncero Cesar, Valdivieso M-Henar, Duran Angel, Popolo Laura
Abstract excerpt
Chitin synthase III is essential for the increase in chitin level and for cell integrity in cells lacking Gas1p, a beta(1,3)-glucanosyltransferase. In order to discover whether the upregulation of chitin synthesis proceeds through the canonical transport and activation pathway of Chs3p or through an alternative one, here we studied the effects of the inactivation of the GAS1 and CHS4-5-6-7 genes. All the...
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