Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chitin synthase III: synthetic lethal mutants and "stress related" chitin synthesis that bypasses the CSD3/CHS6 localization pathway.

Proceedings of the National Academy of Sciences of the United States of America - 28 Sept 1999

Osmond B C, Specht C A, Robbins P W

Abstract excerpt

We screened Saccharomyces strains for mutants that are synthetically lethal with deletion of the major chitin synthase gene CHS3. In addition to finding, not surprisingly, that mutations in major cell wall-related genes such as FKS1 (glucan synthase) and mutations in any of the Golgi glycosylation complex genes (MNN9 family) are lethal in combination with chs3Delta, we found that a mutation in Srv2p, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Wall
Share to Chitin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chitin Synthase

Share to Diffusion

Share to Echinocandins

Share to Glucosyltransferases

Share to Microfilament Proteins

Share to Schizosaccharomyces pombe Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 10500155
DOI: 10.1073/pnas.96.20.11206
PMCID: PMC18012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chitin synthase III: synthetic lethal mutants and "stress related" chitin synthesis that bypasses the CSD3/CHS6 localization pathway.PMID 10500155Read ↗

An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae.Semantic proximity Read ↗

Chitin synthesis in Saccharomyces cerevisiae in response to supplementation of growth medium with glucosamine and cell wall stress.Semantic proximity Read ↗

Chitin synthase I and chitin synthase II are not required for chitin synthesis in vivo in Saccharomyces cerevisiae.Semantic proximity Read ↗

Maintenance of cell integrity in the gas1 mutant of Saccharomyces cerevisiae requires the Chs3p-targeting and activation pathway and involves an unusual Chs3p localization.Semantic proximity Read ↗

Molecular analysis of Chs3p participation in chitin synthase III activity.Semantic proximity Read ↗

The chsD and chsE genes of Aspergillus nidulans and their roles in chitin synthesis.Semantic proximity Read ↗

The fission yeast SEL1 domain protein Cfh3p: a novel regulator of the glucan synthase Bgs1p whose function is more relevant under stress conditions.Semantic proximity Read ↗

Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin.Semantic proximity Read ↗

The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle.Semantic proximity Read ↗

The Candida albicans CHS4 gene complements a Saccharomyces cerevisiae skt5/chs4 mutation and is involved in chitin biosynthesis.Semantic proximity Read ↗

Chitin synthesis in a gas1 mutant of Saccharomyces cerevisiae.Semantic proximity Read ↗

Subcellular localization, abundance and stability of chitin synthetases 1 and 2 from Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.