Article
Chitin synthesis in Saccharomyces cerevisiae in response to supplementation of growth medium with glucosamine and cell wall stress.
Eukaryotic cell - 1 Oct 2003
Bulik Dorota A, Olczak Mariusz, Lucero Hector A, Osmond Barbara C, Robbins Phillips W, Specht Charles A
Abstract excerpt
In Saccharomyces cerevisiae most chitin is synthesized by Chs3p, which deposits chitin in the lateral cell wall and in the bud-neck region during cell division. We have recently found that addition of glucosamine (GlcN) to the growth medium leads to a three- to fourfold increase in cell wall chitin levels. We compared this result to the increases in cellular chitin levels associated with cell wall stress and with...
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