Article
The genetic interaction network of CCW12, a Saccharomyces cerevisiae gene required for cell wall integrity during budding and formation of mating projections.
BMC genomics - 14 Feb 2011
Ragni Enrico, Piberger Heidi, Neupert Christine, García-Cantalejo Jesús, Popolo Laura, Arroyo Javier, Aebi Markus, Strahl Sabine
Abstract excerpt
BACKGROUND: Mannoproteins construct the outer cover of the fungal cell wall. The covalently linked cell wall protein Ccw12p is an abundant mannoprotein. It is considered as crucial structural cell wall component since in baker's yeast the lack of CCW12 results in severe cell wall damage and reduced mating efficiency. RESULTS: In order to explore the function of CCW12, we performed a Synthetic Genetic Analysis...
Topics
- Cell Wall
- DNA, Fungal
- Gene Expression Profiling
- Gene Expression Regulation, Fungal
- Gene Regulatory Networks
- Membrane Glycoproteins
- Mutation
- Oligonucleotide Array Sequence Analysis
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins