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Targeting Epidermal Growth Factor Receptor–Associated Signaling Pathways in Non–Small Cell Lung Cancer Cells: Implication in Radiation Response

29 Jun 2010

Abstract excerpt

Several studies have shown solid evidence for the potential value of targeting epidermal growth factor receptor (EGFR) signaling to enhance the antitumor activity of radiation. However, therapeutic resistance has emerged as an important clinical issue. Here, we investigated whether strategies for targeting EGFR-associated downstream signaling would radiosensitize a panel of non-small cell lung cancer cell lines....

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Share to Cancer therapeutics and mechanisms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20587532
DOI: 10.1158/1541-7786.mcr-09-0507

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