Article
Functional polymorphism of the NFKB1 gene promoter is not relevant in predisposition to celiac disease.
Scandinavian journal of gastroenterology - 1 Apr 2006
Rueda Blanca, Núñez Concepción, López-Nevot Miguel A, Paz Ruiz Maria, Urcelay Elena, De la Concha Emilio G, Martín Javier
Abstract excerpt
OBJECTIVE: The nuclear factor (NF)-kappaB is one of the pivotal regulators of autoimmunity and inflammation, which has been shown to be activated in the inflamed mucosa of patients with celiac disease (CD). Recently, in the NFKB1 gene promoter region, a common insertion/deletion (-94ins/delATTG)...
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