Article
Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice.
Proceedings of the National Academy of Sciences of the United States of America - 22 Feb 2005
Haines Jackie, Johnson Victoria, Pack Kevin, Suraweera Nirosha, Slijepcevic Predrag, Cabuy Erik, Coster Margaret, Ilyas Mohammad, Wilding Jennifer, Sieber Oliver, Bodmer Walter, Tomlinson Ian, Silver Andrew
Abstract excerpt
Apc(Min) mice have provided an example of a locus (Modifier of Min1; Mom1) modifying adenoma numbers in the intestines of inbred strains. Linkage analysis located Mom1 on chromosome 4, and further investigation identified secretory phospholipase A2 (Pla2g2a) as a candidate gene. Because of unknow...
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