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Article

Phosphoinositide binding regulates alpha-actinin dynamics: mechanism for modulating cytoskeletal remodeling.

The Journal of biological chemistry - 15 Apr 2005

Fraley Tamara S, Pereira Clifford B, Tran Thuan C, Singleton CoreyAyne, Greenwood Jeffrey A

Abstract excerpt

The active association-dissociation of dynamic protein-protein interactions is critical for the ability of the actin cytoskeleton to remodel. To determine the influence of phosphoinositide binding on the dynamic interaction of alpha-actinin with actin filaments and integrin adhesion receptors, fluorescence recovery after photobleaching (FRAP) microscopy was carried out comparing wild-type green fluorescent...

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Identifiers

PMID: 15710624
DOI: 10.1074/jbc.M500631200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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