Article
Modulating alpha-actinin-4 dynamics in podocytes.
Cell motility and the cytoskeleton - 1 Mar 2009
Michaud Jean-Louis R, Hosseini-Abardeh Mona, Farah Kevin, Kennedy Chris R J
Abstract excerpt
Podocytes are epithelial cells that line the outer aspect of renal blood vessels and provide a platform for the kidney's filtering apparatus, the slit diaphragm. Mutations in alpha-actinin-4, an actin bundling protein highly expressed in podocytes, result in increased affinity for actin and cause...
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