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Article

Characterization of nucleosomes consisting of the human testis/sperm-specific histone H2B variant (hTSH2B).

Biochemistry - 22 Feb 2005

Li Andra, Maffey Allison H, Abbott Wade D, Conde e Silva Natalia, Prunell Ariel, Siino Joseph, Churikov Dmitrii, Zalensky Andrei O, Ausió Juan

Abstract excerpt

We have reported earlier the occurrence of a specific histone H2B variant in human testis and sperm. Here we have structurally characterized this protein, its association with the rest of the histone octamer, and its effects on the nucleosome structure. We show that a reconstituted octamer consisting of hTSH2B and a stoichiometric complement of histones H2A, H3, and H4 exhibits a lower stability compared to the...

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PMID: 15709765
DOI: 10.1021/bi048061n

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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