Article
The NH2 tail of the novel histone variant H2BFWT exhibits properties distinct from conventional H2B with respect to the assembly of mitotic chromosomes.
Molecular and cellular biology - 1 Feb 2006
Boulard Mathieu, Gautier Thierry, Mbele Gaelh Ouengue, Gerson Véronique, Hamiche Ali, Angelov Dimitar, Bouvet Philippe, Dimitrov Stefan
Abstract excerpt
We have studied the functional and structural properties of nucleosomes reconstituted with H2BFWT, a recently identified putative histone variant of the H2B family with totally unknown function. We show that H2BFWT can replace the conventional histone H2B in the nucleosome. The presence of H2BFWT did not affect the overall structure of the nucleosome, and the H2BFWT nucleosomes exhibited the same stability as...
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