Article
Growth of hepatitis A virus in a mouse liver cell line.
Journal of virology - 1 Mar 2005
Feigelstock Dino A, Thompson Peter, Kaplan Gerardo G
Abstract excerpt
Hepatitis A virus (HAV) has been adapted to grow efficiently in primate and some nonprimate cell lines but not in cells of murine origin. To understand the inability of the virus to grow in mouse cells, we studied the replication of HAV in immortalized and nontransformed MMH-D3 mouse liver cells, which require growth factors and collagen to maintain their phenotype. HAV grew in MMH-D3 cells transfected with...
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