Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus.

Hepatology (Baltimore, Md.) - 1 Nov 2005

Tsuge Masataka, Hiraga Nobuhiko, Takaishi Hideki, Noguchi Chiemi, Oga Hiromi, Imamura Michio, Takahashi Shoichi, Iwao Eiji, Fujimoto Yoshifumi, Ochi Hidenori, Chayama Kazuaki, Tateno Chise, Yoshizato Katsutoshi

Abstract excerpt

Studies of hepatitis B virus (HBV) mutants have been hampered by the lack of a small animal model with long-term infection of cloned HBV. Using a mouse model in which liver cells were highly replaced with human hepatocytes that survived over a long time with mature human hepatocyte function, we p...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chimera
Share to Genetic Engineering
Share to Hepatitis B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B virus

Share to Hepatocytes

Share to Histocytochemistry

Share to Lamivudine

Share to Viremia

Source

Identifiers

PMID: 16250045
DOI: 10.1002/hep.20892

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16250045-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus.PMID 16250045Read ↗

Are Humanized Mouse Models Useful for Basic Research of Hepatocarcinogenesis through Chronic Hepatitis B Virus Infection?Semantic proximity Read ↗

Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon.Semantic proximity Read ↗

Animal models for the study of HBV replication and its variants.Semantic proximity Read ↗

New horizons for studying human hepatotropic infectionsSemantic proximity Read ↗

Liver humanized NSG-PiZ mice support the study of chronic hepatitis B virus infection and antiviral therapiesSemantic proximity Read ↗

Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma.Semantic proximity Read ↗

A Chimeric Humanized Mouse Model by Engrafting the Human Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cell for the Chronic Hepatitis B Virus InfectionSemantic proximity Read ↗

Cell culture and animal models of viral hepatitis. Part I: hepatitis B.Semantic proximity Read ↗

A genetically humanized mouse model for hepatitis C virus infection.Semantic proximity Read ↗

Small Animal Model Systems for Studying Hepatitis B Virus Replication and PathogenesisSemantic proximity Read ↗

Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatmentSemantic proximity Read ↗

In Vivo Mouse Models for Hepatitis B Virus Infection and Their ApplicationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.