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Article

A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense.

The Journal of biological chemistry - 15 Apr 2005

Gronert Karsten, Maheshwari Neha, Khan Nabeela, Hassan Iram R, Dunn Michael, Laniado Schwartzman Michal

Abstract excerpt

The surface of the eye actively suppresses inflammation while maintaining a remarkable capacity for epithelial wound repair. Our understanding of mechanisms that balance inflammatory/reparative responses to provide effective host defense while preserving tissue function is limited, in particular, in the cornea. Lipoxin A(4) (LXA(4)) and docosahexaenoic acid-derived neuroprotectin D1 (NPD1) are lipid autacoids...

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Source

Identifiers

PMID: 15708862
DOI: 10.1074/jbc.M410638200

Genes

LOX
LTB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense.PMID 15708862Read ↗

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