Article
Association between the DRD2 A1 allele and opium addiction in the Iranian population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2005
Shahmoradgoli Najafabadi Maria, Ohadi Mina, Joghataie Mohammad Taghi, Valaie Faraz, Riazalhosseini Yasser, Mostafavi Hamid, Mohammadbeigi Fariba, Najmabadi Hossein
Abstract excerpt
Dysfunction of the central dopaminergic neurotransmission has been suggested to play an important role in the etiology of certain neuropsychiatric disorders such as drug abuse. It has been shown that the dopamine D2 receptor (DRD2) gene dysfunction is associated with multi-drug addiction. Addiction to opium is the most common form of drug abuse in Iran. We studied the allelic association between DRD2 Taq I A...
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