Article
Gender effect on association between DRD2 polymorphism and substance dependence in a Spanish sample.
Drug and alcohol dependence - 1 May 2009
López-Castromán Jorge, Vaquero-Lorenzo Concepcion, Perez-Rodriguez M Mercedes, Diaz-Hernandez Montserrat, Fernandez-Piqueras Jose, Saiz-Ruiz Jeronimo, Baca-Garcia Enrique
Abstract excerpt
Our aim was to examine a possible association between substance dependence and the TaqIA polymorphism of the D2 dopamine receptor (DRD2), a single nucleotide polymorphism (SNP) located at the 3' UTR region of the DRD2 gene. A case-control design stratified by gender was used to analyze the genotypes of this SNP in a sample of 125 substance-dependent patients according to DSM-IV and 203 blood donors recruited as...
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