Article
Polymorphisms in the interleukin 17F gene (IL17F) and asthma.
Genes and immunity - 1 May 2005
Ramsey C D, Lazarus R, Camargo C A, Weiss S T, Celedón J C
Abstract excerpt
Interleukin17F (IL17F) is a regulatory cytokine for T-cell-mediated immune responses. The gene coding for IL17F (IL17F) is located on chromosome 6p, a genomic region linked to asthma and asthma-related phenotypes in multiple genome scans. IL17F is expressed in lung tissue, in bronchoalveolar lavage fluid from asthmatic subjects, and in activated CD4+ cells. We were thus interested in testing for association...
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