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Article

RhoA and Rac mediate endothelial cell polarization and detachment induced by T-cadherin.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Apr 2005

Philippova Maria, Ivanov Danila, Allenspach Roy, Takuwa Yoh, Erne Paul, Resink Thérèse

Abstract excerpt

T-cadherin (T-cad) is an atypical GPI-anchored member of the cadherin superfamily. Ligation of T-cad receptors on endothelial cells prevents cell spreading, promotes elongation and polarization, decreases adhesion to the matrix, and facilitates migration. This study investigates involvement of Rho GTPases in T-cad signaling. Human umbilical vein endothelial cells were infected with adenoviral vectors expressing...

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Source

Identifiers

PMID: 15703273
DOI: 10.1096/fj.04-2430fje

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CAT
GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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