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Article

Association study with Wegener granulomatosis of the human phospholipase Cgamma2 gene.

Journal of negative results in biomedicine - 9 Feb 2005

Jagiello Peter, Wieczorek Stefan, Yu Philipp, Csernok Elena, Gross Wolfgang L, Epplen Joerg T

Abstract excerpt

BACKGROUND: Wegener Granulomatosis (WG) is a multifactorial disease of yet unknown aetiology characterized by granulomata of the respiratory tract and systemic necrotizing vasculitis. Analyses of candidate genes revealed several associations, e.g. with alpha(1)-antitrypsin, proteinase 3 and with the HLA-DPB1 locus. A mutation in the abnormal limb mutant 5 (ALI5) mouse in the region coding for the hydrophobic...

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Identifiers

PMID: 15703080
DOI: 10.1186/1477-5751-4-1
PMCID: PMC549077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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