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Article

An analysis of CTLA-4 and proinflammatory cytokine genes in Wegener's granulomatosis.

Arthritis and rheumatism - 1 Aug 2004

Zhou Yihua, Huang DeRen, Paris Pamela L, Sauter Craig S, Prock Kristin A, Hoffman Gary S

Abstract excerpt

OBJECTIVE: The precipitating event(s) that triggers Wegener's granulomatosis (WG) is unknown. Cytokines, costimulatory molecules, and counterregulatory molecules control the quality and intensity of immune responses. Thus, they are relevant candidates for genetic studies of immune dysregulation in WG, the pathogenesis of which may be facilitated by multiple acquired and/or inherited factors. This study was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15334480
DOI: 10.1002/art.20385

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An analysis of CTLA-4 and proinflammatory cytokine genes in Wegener's granulomatosis.PMID 15334480Read ↗

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